Wiki calcium ascorbate
Ascorbic Acid is commonly called Vitamin C.
Calcium Ascorbate in Food
Calcium Ascorbate and Magnesium Ascorbate are described as antioxidants and skin conditioning agents--miscellaneous for use in cosmetics, but are not currently used. Sodium Ascorbyl Phosphate functions as an antioxidant in cosmetic products and is used at concentrations ranging from 0.
Magnesium Ascorbyl Phosphate functions as an antioxidant in cosmetics and was reported being used at concentrations from 0. Sodium Ascorbate also functions as an antioxidant in cosmetics at concentrations from 0. L-Ascorbic Acid is readily and reversibly oxidized to L-dehydroascorbic acid and both forms exist in equilibrium in the body.
Permeation rates of Ascorbic Acid through whole and stripped mouse skin were 3. Acute oral and parenteral studies in mice, rats, rabbits, guinea pigs, dogs, and cats demonstrated little toxicity. Ascorbic Acid and Sodium Ascorbate acted as a nitrosation inhibitor in several food and cosmetic product studies.
No compound-related clinical signs or gross or microscopic pathological effects were observed in either mice, rats, or guinea pigs in short-term studies.
Male guinea pigs fed a control basal diet and given up to mg Ascorbic Acid orally for 20 weeks had similar hemoglobin, blood glucose, serum iron, liver iron, and liver glycogen levels compared to control values. Ascorbic Acid was a photoprotectant when applied to mice and pig skin before exposure to ultraviolet UV radiation. The inhibition of UV-induced suppression of contact hypersensitivity was also noted. Magnesium Ascorbyl Phosphate administration immediately after exposure in hairless mice significantly delayed skin tumor formation and hyperplasia induced by chronic exposure to UV radiation.
Ascorbic Acid and Sodium Ascorbate were not genotoxic in several bacterial and mammalian test systems, consistent with the antioxidant properties of these chemicals. In the presence of certain enzyme systems or metal ions, evidence of genotoxicity was seen. Ascorbic Acid was not carcinogenic in either sex of both rats and mice. Inhibition of carcinogenesis and tumor growth related to Ascorbic Acid's antioxidant properties has been reported. Sodium Ascorbate has been shown to promote the development of urinary carcinomas in two-stage carcinogenesis studies.
Dermal application of Ascorbic Acid to patients with radiation dermatitis and burn victims had no adverse effects. Because of the structural and functional similarities of these ingredients, the Panel believes that the data on one ingredient can be extrapolated to all of them. The Expert Panel attributed the finding that Ascorbic Acid was genotoxic in these few assay systems due to the presence of other chemicals, e.
Supporting this view were the carcinogenicity studies conducted by the NTP, which demonstrated no evidence of carcinogenicity. Ascorbic Acid was found to effectively inhibit nitrosamine yield in several test systems.
The Panel did review studies in which Sodium Ascorbate acted as a tumor promoter in animals. These results were considered to be related to the concentration of sodium ions and the pH of urine in the test animals. Similar effects were seen with sodium bicarbonate. Because of the concern that certain metal ions may combine with these ingredients to produce pro-oxidant activity, the Panel cautioned formulators to be certain that these ingredients are acting as antioxidants in cosmetic formulations.
These data coupled with an absence of reports in the clinical literature of Ascorbic Acid sensitization strongly support the safety of these ingredients. Publication types Review.
Substances Cosmetics Irritants Ascorbic Acid.Medically reviewed by Drugs. Last updated on Aug 3, Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. You must check to make sure that it is safe for you to take calcium ascorbate with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. Use calcium ascorbate as ordered by your doctor.
Read all information given to you. Follow all instructions closely. Ascorbic acid dosage information in more detail. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:.
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Subscribe to Drugs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Skip to Content. Calcium Ascorbate. See also: Ascorbic acid dosage information in more detail.Both calcium and vitamin C are important for proper health.
Calcium helps build strong bones and teeth, and vitamin C boosts your immune system. Unfortunately, vitamin C, when taken alone, can deplete calcium stores in your body, and can often be too acidic to be tolerated by people with sensitive stomachs. Calcium ascorbate overcomes these problems. Calcium ascorbate combines ascorbic acid, also known as vitamin C, with the mineral calcium into a single pill. This natural form of vitamin C is a neutral salt, not an acid. Digesting calcium ascorbate in your stomach releases calcium and the ascorbate ions.
The acid in your stomach converts the ascorbate ions into ascorbic acid, resulting in no net increase in the acid concentration in your stomach. This is particularly beneficial for people with sensitive stomachs and for the severely ill, who may be weak and nauseated but most in need of vitamin C and calcium supplementation.
In addition, calcium ascorbate can be taken at higher doses with decreased side effects seen with vitamin C supplementation alone, including loose stools and stomachaches.
Combining two supplements into one pill provides convenience. When you need two different types of vitamin and mineral supplementation, swallowing one pill is easier than swallowing two. In addition, buying one pill that satisfies both needs is more cost-effective than buying two separate pills. Vitamin and mineral supplementation often falls short because your body is unable to absorb the nutrients in the form provided by the supplement.
Because calcium ascorbate is a natural form of vitamin C, it has been suggested that much more vitamin C is absorbed in the bloodstream than the other forms. However, according to the Linus Pauling Institute, the only published study in humans addressing this issue found no difference between a commercially available calcium ascorbate and ascorbic acid tablets in terms of vitamin C absorption.
However, according to Dr. Sears, a well-known pediatrician and the author of several medical books, the reverse may be true; vitamin C may actually improve the absorption of calcium. Nutrition Nutrition Basics Vitamins and Supplements. What Are the Benefits of Calcium Ascorbate?
By Robin Wasserman.Calcium ascorbate is a common food additive with valuable antioxidant properties. Often used as a preservative, calcium ascorbate can extend the shelf life of food and beverage products and protect against deterioration of color, flavor, and overall quality. As a type of vitamin C, calcium ascorbate also offers health benefits, such as improving immune functioning, repairing damaged tissues, and promoting bone, teeth, and skin health.
Calcium ascorbate is a natural food additive that can produce healthy, clean-label foods and beverages to meet the growing demand of health-conscious consumers.
Mineral ascorbates are salts that come from ascorbic acid, commonly known as vitamin C. Ascorbates from vitamin C come in several iterations, including calcium ascorbate, sodium ascorbate, magnesium ascorbate, and potassium ascorbate.
Each type of vitamin C ascorbate contains a positively charged cation and a negatively charged ascorbate anion, so calcium ascorbate contains an ascorbate anion and a calcium ion. Because the ascorbate anion is the active part of each compound, mineral ascorbates exhibit many of the same beneficial properties as vitamin C. As an essential vitamin for humans, vitamin C plays an important role in maintaining healthy skin, teeth, bones, cartilage, and tissues.
Vitamin C aids in immune system function, repairs tissues, and helps some enzymes work better. Because of its antioxidant properties, vitamin C also protects the cells against damage from free radicals. The stabilizing properties and various health benefits of calcium ascorbate make it a useful ingredient in many different products.
Calcium ascorbate is primarily an additive in the food and beverage industrybut also has applications in cosmeticsskin carepharmaceuticalsand as an ingredient in animal feed. In the food and beverage industry, calcium ascorbate is a common food additive for its health benefits or as a stabilizing agent. Fortifying foods with calcium ascorbate boosts their vitamin C content, which can make up for vitamin C depletion that occurs during processing.
Food manufacturers often add calcium ascorbate to orange juice or other fruit juices after they pasteurize them to replenish their vitamin C content. Calcium ascorbate can also increase the calcium content in products like ice cream or yogurt.
As a stabilizer, calcium ascorbate preserves the color and freshness of food and beverage products to extend their shelf life and stability. Because calcium ascorbate has a low pH, it helps prevent microbial growth which can lead to spoilage or cause food to become contaminated. Calcium ascorbate is popular as a food preservative because it is a natural alternative to harsher chemical preservatives.
The Food and Drug Administration lists calcium ascorbate as a generally-recognized-as-safe substance as a food additive, preservative, or nutrient supplement. Because it is safe for human consumption and does not harm the environment, calcium ascorbate can also be a safe additive in animal feed or water. In the cosmetics industryascorbates play an essential role as antioxidants in many skin care products, including lotions, moisturizers, creams, cleansers, and sunscreen.
Calcium ascorbate is also a skin conditioning agent that can slow the signs of aging and preserve the youthful appearance of the skin, which is why it is a common ingredient in anti-aging cosmetic lotions and eye cream.
Calcium ascorbate also has lightening properties and is common in skin lightening spot treatments that reduce the appearance of discoloration. Outside of the skin care segment of the cosmetics industry, calcium ascorbate is a common ingredient in some makeup products, mouthwash, and whitening toothpaste.Vitamin Calso known as ascorbic acid and ascorbateis a vitamin found in various foods and sold as a dietary supplement. There is some evidence that regular use of supplements may reduce the duration of the common coldbut it does not appear to prevent infection.
Vitamin C is generally well tolerated. Vitamin C was discovered inisolated inand inwas the first vitamin to be chemically produced. Vitamin C is an essential nutrient for certain animals including humans. The term vitamin C encompasses several vitamers that have vitamin C activity in animals. Ascorbate salts such as sodium ascorbate and calcium ascorbate are used in some dietary supplements. These release ascorbate upon digestion. Ascorbate and ascorbic acid are both naturally present in the body, since the forms interconvert according to pH.
Oxidized forms of the molecule such as dehydroascorbic acid are converted back to ascorbic acid by reducing agents. Vitamin C functions as a cofactor in many enzymatic reactions in animals including humans that mediate a variety of essential biological functions, including wound healing and collagen synthesis.
In humans, vitamin C deficiency leads to impaired collagen synthesis, contributing to the more severe symptoms of scurvy. These compounds can be restored to a reduced state by glutathione and NADPH -dependent enzymatic mechanisms. In plants, vitamin C is a substrate for ascorbate peroxidase. This enzyme utilizes ascorbate to neutralize excess hydrogen peroxide H 2 O 2 by converting it to water H 2 O and oxygen. The percent of people reported as deficient was 7. Scurvy is a disease resulting from a deficiency of vitamin C.
Without this vitamin, collagen made by the body is too unstable to perform its function and several other enzymes in the body do not operate correctly. The skin lesions are most abundant on the thighs and legs, and a person with the ailment looks pale, feels depressed, and is partially immobilized. In advanced scurvy there are open, suppurating woundsloss of teethbone abnormalities and, eventually, death.
Notable human dietary studies of experimentally induced scurvy were conducted on conscientious objectors during World War II in Britain and on Iowa state prisoners in the late s to the s. Men in both studies had blood levels of ascorbic acid too low to be accurately measured by the time they developed signs of scurvy.
Vitamin C has a definitive role in treating scurvy, which is a disease caused by vitamin C deficiency. Beyond that, a role for vitamin C as prevention or treatment for various diseases is disputed, with reviews reporting conflicting results.In the event of a fixture, map or round starting but not being completed, bets will be void unless the outcome is already determined.
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What Are the Benefits of Calcium Ascorbate?
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